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Okadaic acid br observed under a fluorescence
2020-08-07
observed under a 200 □ fluorescence inverted microscope, because the CT Okadaic acid and ATF-CAR T cells were in the same morphology; therefore, the CT image is not shown. Cell phenotype was analyzed 7 days after transduction (10 days for in vitro culture), with the logarithmic am-plification of C
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br In this study as it shown in
2020-08-07
In this study, as it shown in Fig. 7, we developed LMNs that could significantly inhibit breast cancer cell growth through both photo-dynamic therapy and chemotherapy. The LMNs exhibited a high drug loading and encapsulation efficiency for both DOX and HMME. In vitro drug release studies have demons
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br Our study has some limitations
2020-08-07
Our study has some limitations. NORMO data for physical activity are self-reported, and it is well known that people tend to overestimate their level of physical activity [33]. In the collection of data, the participants were told to round the level of both moderate and vigorous activities to the
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br TP INP overexpression resulted in
2020-08-07
TP53INP2 overexpression resulted in a trend toward increased cancer-induced muscle loss also in female mice, at both early and late stages of cachexia (Fig. S3). To understand the molecular alterations associat-ed with muscle wasting in WT and Tg TB mice, the Haloperidol of relevant genes was
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br Introduction b iframe width
2020-08-05
1. Introduction r> Colorectal cancer (CRC) is the third most common malignancy worldwide. Surgical removal of the tumor is the only curative treat-ment, but still 30–40% of patients with potentially curable CRC relapses [1]. Diabetes mellitus and colorectal cancer share several risk factors incl
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br The quantification of ML and VT
2020-08-02
The quantification of ML and VT contents in the preparation are detailed by Pfüller and Schumacher (2016). Iscucin® Salicis and Tiliae delivered high, Crataegi, Populi and Mali middle and Abietis and Pini low content of ML-1, analysed by ELISA. A high value of VT-A was mea-sured in Iscucin® Cratae
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br cell cycle Apart anticancer
2020-08-02
cell cycle [24,18]. Apart, anticancer potential of fucoidan was explored by the increase of immune response signaling molecules like inter-leukins (IL-2, IL-12) and interferon gamma (IFN-γ) [12]. Thus, immune-therapy potential of fucoidan was proven through intruding AMG-176 pro-liferation by i
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S Kossatz J Grandke P Couleaud A Latorre
2020-08-02
[30] S. Kossatz, J. Grandke, P. Couleaud, A. Latorre, A. Aires, K. Crosbie-Staunton, R. Ludwig, H. Dähring, V. Ettelt, A. Lazaro-Carrillo, Efficient treatment of breast cancer xenografts with multifunctionalized iron oxide nanoparticles combining magnetic hyperthermia and anti-cancer drug delivery, Br
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Bradykinin (acetate) br Cell transfection and selection of s
2020-07-31
2.2. Cell transfection and selection of stable dupa7-Myc transfectants The dupα7.pcDNA3.1/Myc-His construct used for transfection was prepared in our laboratory as described elsewhere [20]; it contains the full-length human dupα7 cDNA sequence in frame with the Myc-His tag. The A549 or SK-MES-1
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br Carotene concentrations in both extracts br The levels of
2020-07-31
3.6. β-Carotene concentrations in both extracts The levels of β-carotene, which is known as one of major car-otenoids in Chinese cabbage, were measured in TL and NL by HPLC. β-Carotene was found at 40.5 min retention time (RT), and regarding its concentration, TL extract contained 27.9 ± 2.1 μg
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br Conclusions Claudin is a useful
2020-07-30
Conclusions: Claudin-1 is a useful target for near-infrared antibody-based imaging for visualization of colorectal tumors for future use in fluorescence-guided surgery. Published by Elsevier Inc. Presented at the 13th Annual Academic Surgical Congress, Houston, TX, February 5-7, 2019. Int
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br Living organisms are continuously exposed to background i
2020-07-29
Living organisms are continuously exposed to background ionizing radiation emitted from either natural or man-made radiation sources. Effects from radiation usually fall under the category of stochastic effects (Flynn and Theodore, 2002). Cancer and genetic effects are the two most common possi
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Filipin III br SPDEF transcriptionally represses ZBTB in pro
2020-07-29
3.2. SPDEF transcriptionally represses ZBTB46 in prostate cancer cells Unlike luminal-type tumor cells, NE Filipin III do not express AR, and AR signaling is repressed [12]. We next validated ZBTB46 expression in the Cancer Genome Atlas (TCGA) prostate dataset by a gene set enrichment analys
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br These previous two points suggest that
2020-07-29
These previous two points suggest that the observed AHR for OS associated with ADT use underestimates the true survival benefit of ADT for both Gleason 8 and 9–10 patients. However, our findings of significant interactions between ADT and Gleason score, which indicate that any survival advantage f
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br Phosphatase overexpression can drive tumor progression
2020-07-28
Phosphatase overexpression can drive tumor progression, but the underlying signaling mechanisms have been unclear (Ju-lien et al., 2011). Our data indicate that rather than directly acti-vating a cancer-driving signaling pathway, the overexpression of ERK-specific phosphatases modulates signaling