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br miR p Transferred by BMSC Derived Exosomes
2021-03-03
miR-126-3p Transferred by BMSC-Derived Exosomes Suppresses Proliferation, Migration, and Invasion of Pancreatic Cancer Cells and Enhances Their Apoptosis In order to examine the effect of miR-126-3p in BMSC-derived exo-somes on the biological function of pancreatic cancer cells, the cell
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br Results br This analysis included
2021-03-03
3. Results This analysis included 708 black and 651 white men recruited from urology clinics in Nashville, TN or Durham, NC. White men were older Table 1 Description of black and white men in study population. Black White Pc a PSA data were not collected from Duke/Durham VA site.
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br In vivo experiments br
2021-03-03
2.4. In vivo experiments 2.4.1. Tumor model establishment Female sever combined immunodeficient (SCID) mice (4–5 weeks old) were purchased from the Sun Yat-sen University Laboratory Animal Center and fed in an SPF (specific pathogen free) class experi-mental animal room. The protocols for in
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HG-9-91-01 br The in vitro evaluation of the synthesized
2021-03-03
The in vitro evaluation of the synthesized conjugates was performed in human lung cancer cells, A549 which were procured from National Center for Cell Sciences (NCCS, Pune, India). Cells were grown in Dulbecco’s minimum essential medium (DMEM) containing 10% FBS and 1% penicillin-streptomycin solu
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br Materials and methods br SUN base was provided
2021-03-03
2. Materials and methods SUN base was provided by Parsian Pharmaceutical Co (Iran). Pluronic F127 (PF127), coumarin 6 (C6), biotin, cholesterol (Chol), stearylamine, anhydrous dimethyl sulfoxide (DMSO), 4- N-hydro-xysuccinimide (NHS), dicyclohexylcarbodiimide (DCC), and dialysis bag (molecular
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br wrap them Videos S S S and S
2021-03-03
wrap them (Videos S4, S5, S6, and S7, SI). Both MIA Cycloheximide and PSCs in co-culture actively migrated on CS-HA coated plates, especially when the ratio of PSCs increased (Fig. S6, SI). The moving patterns (trajec-tories) of MIA cells alone and PSCs alone are shown in Fig. 3B. The moving patt
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br of immune responses Balasse et al Balasse
2020-08-30
of immune responses (Balasse et al., 2008). Balasse et al. reported that the injection route of nanoparticles affected the quality of immune re-sponses due to differences in frequency and population type of APCs at the injection sites. During intraperitoneal (i.p) and s.c immunization, the injected
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br Programmed death ligand PD L also known as
2020-08-30
Programmed death-ligand 1 (PD-L1, also known as CD274 and B7-H1) is a critical “don't find me” signal to the adaptive immune system. Upregulation of PD-L1 is another strategy for tumor ASP1517 to evade the immune system. The suppression of PD-L1 to elicit an immune response against tumors has bee
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FG4592 br E mail addresses jenny aasa aces su se J
2020-08-28
E-mail addresses: [email protected] (J. Aasa), [email protected] (M. Törnqvist). benchmark dose at the lower bound (BMDL) is compared to human intake estimates (EFSA, 2005). Although uncertainties in the extra-polation of risks from high exposure doses in animals to lower expos
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br Our current study suggested that CA can preceded the
2020-08-28
Our current study suggested that CA19-9 can preceded the radiological appearance by about 3 months and tumor marker-guided early salvage therapy can delay disease progression and prolong overall survival of patients receiving resection. In patients who started their salvage treatment early, the me
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br INTRODUCTION br Most cells
2020-08-18
INTRODUCTION Most Elafibranor that are able to adhere, spread, and migrate on a two-dimensional extracellular matrix (ECM) can also adhere, change shape, and migrate when embedded in a biopolymer network of suitable adhesiveness, stiffness, and network porosity. However, when cells migrate thr
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Hypromellose br Information about the participant s diet was
2020-08-18
Information about the participant's diet was collected using a three day food diary. Parents or participants were asked to record all they ate and drank on three consecutive days (2 weekdays and 1 weekend day). Participants were given written and verbal in-structions to complete the diary and were
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PF06424439 br To further confirm that TRIM
2020-08-18
To further confirm that TRIM25 expression is regulated by miR-3614-3p, we generated MCF-7 and MDA-MB-231 cell lines stably ex-pressing miR-3614 (LV-miR-3614) or transiently transfected with a pre-miR-3614 plasmid, which exhibits a high expression level of miR-3614 compared to that of the control.
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br CONFLICTS OF INTEREST br The authors
2020-08-18
CONFLICTS OF INTEREST The authors have no conflicts of interest. ACKNOWLEDGMENTS We thank Sagetis Biotech for kindly providing oligopeptide-modified poly(b-amino ester)s (OM-pBAE) polymers. This work was devel-oped at the Centro Esther Koplowitz, Barcelona, Spain. M.R.-R. and G.R. are rec
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br Of note increased risk
2020-08-18
Of note, increased risk was seen with PSA levels of 1.1– 1.7 ng/ml at ages 40–54 yr, well within the “normal” range, and low enough not to trigger follow-up in usual clinical practice. These findings do not imply that prostate biopsy or definitive treatment is immediately required in younger men w